|
Dear visitor:
In this section we
will be adding selected medical articles related to obesity and/or hCG
in order to establish a preliminary bibliography for the Symposium and
Training Program.
Estimado visitante:
En esta sección iremos agregando artículos seleccionados de la
bibliografía médica relacionados con el tema de la obesidad y/o hCG a
fin de conformar un cuerpo de conocimientos preliminar para el Simposio
y Programa de Entrenamiento.
Questions /
Comments:
Please address your questions to
info@oralhcg.com
|
In English
|
|
|
|
|
Obesity assessment
|
1) Sub-cutaneous fat
thickness measured by magnetic resonance imaging, ultrasound,
and calipers. Hayes PA, Sowood PJ et. al. in Med Sci Sports
Exerc. 1988 Jun;20(3):303-9.
Sub-cutaneous fat thickness was measured at 12 sites on the body
surface of 24 males and 26 females using magnetic resonance
imaging (MRI), skinfold calipers, and A-mode ultrasound. A good
between-subject correlation was found between all three methods
in the males but only the calipers and MRI were well correlated
in females.
|
|
2) Obesity: new insight
into the anthropometric classification of fat distribution shown
by computed tomography. Ashwell M, Cole TJ, Dixon AK.
in Br Med J (Clin Res Ed). 1985 Jun 8;290(6483):1692-4.
A high ratio of waist to hip circumference has been shown to
be associated with a high proportion of intra-abdominal fat.
Thus women with a centralised distribution of fat (high waist to
hip ratio: "apples") tend to have a greater proportion of their
fat in the intra-abdominal depot than do women with a peripheral
fat distribution (low waist to hip ratio: "pears").
|
|
|
HCG: General Aspects
|
|
1) Production of a
choriogonadotropin-like factor by a microorganism. In Proc. Natl. Acad.
Sci. USA. Vol. 76, Nº12, pp. 6622-6626, December 1979.
A
microorganism, Progenitor cryptocides, produces a glycoprotein
that is biologically active and has physicochemical properties similar
to those of hCG.
|
|
2) Immunohistochemical localization of
a human chorionic gonadotropin-like subtance in the human pituitary
gland. Suginami H, Kawaoi A. in J Clin Endocrinol Metab 55: 1161-1166,
1982.
The results obtained in the present study and those reported by others
may indicate that the hCG-like substance present in human pituitary
glands is the precursor of hLH.
|
|
3) Human chorionic-like material:
presence in normal human tissues. Yoshimoto Y, Wolfsen AR, Hirose F,
Odell WD. in Am J Obstet Ginecol 134(7): 729-733, 1979.
With the use of radioreceptor assay for gonadotropin and a beta-chain
radioimmunoassay for hCG investigators have been able to demonstrate the
presence of hCG-like material in all normal tissues tested.
|
|
4) Human chorionic gonadotropin-like
substance in nonendocrine tissues of normal subjects. Yoshimoto Y,
Wolfsen AR, Odell WD. in Science. 1977 Aug 5;197(4303):575-7.
Data suggest that the genome responsible for the human chorionic
gonadotropin production is not completely suppressed in adult
nonendocrine tissues, and that the chorionic gonadotropin produced by
colon and liver has little or no bioactivity in vivo because of its low
carbohydrate content. Since many normal tissues produce chorionic
gonadotropin, bioactivity may be modulated by regulation of carbohydrate
content.
|
|
|
|
|
|
|
|
HCG Action
|
|
1) The action of chorionic
gonadotropin in the obese. Dr. ATW Simeons in Lancet II: 946-947, 1954.
Results seem to suggest that hCG plays a rather more important role i
the body's endocrine regulations than has hitherto been assumed; that
there are vitally important reasons for its overproduction in pregnancy;
and that it is in some way specifically concerned with the control of
obesity in both sexes at all ages.
|
2) Metabolic effects of human chorionic gonadotropin (HCG) in rats.
Fleigelman R, Fried GH. in Proc Soc Exp Biol Med. 1970 Nov;135(2):317-9.
For the past 15 year Simeons has used hCG in the treatment of obesity.
Maintenance on a strict 500 cal/day diet and daily injections of hCG
(125 IU) produced weight loss from "abnormal" fat deposits, while
alleviating the sensation of hunger. HCG was believed to act by
mobilizing fat from excessive fat stores in a selective manner. The
present studies suggest an enzimatic basis for this action.
|
3) Chorionic Gonadotrophin
in the treatment of obese women. Dr. ATW Simeons in Am J Clin
Nutr. 1963 Sep;13:197-8.
Letter to the Editor referring to the article "Chorionic
Gonadotrophin in the treatment of obese wwomen" published by
Leela S. Craig in American Journal of Clinical Nutrition, March
1963.
|
4) Human chorionic
gonadotropin in weight reduction (Letter to the editor) Bradley,
P. in Am J Clin Nutr. 1977 May;30(5):649-54.
Letter to the editor from Dr. Patrick Bradley, from Sydney,
Australia.
|
5) Serum
adiponectin levels increase after human chorionic gonadotropin
treatment during in vitro fertilization. Liu YH, Tsai EM, et.
al. in Gynecol Obstet Invest. 2006;62(2):61-5. Epub 2006 Mar 24.
Following gonadotropin treatment, serum adiponectin levels
decrease as a result of the negative effect of high estradiol
levels on adiponectin production. Conversely, serum adiponectin
levels increase following human chorionic gonadotropin treatment.
|
|
6) In vitro effects of
chorionic gonadotropin hormone on human adipose development. Dos
Santos E, Dieudonné MN, et. al. J Endocrinol. 2007
Aug;194(2):313-25.
It is well known that pregnancy is associated with fat weight
gain. However, the mechanisms whereby fat mass accumulation is
controlled during this period are poorly understood. These data
suggest that the pro-adipogenic effect of HCG in human
preadipocytes contributes to explain why increased fat storage
occurs during the first trimester of pregnancy.
|
|
|
|
Miscellaneous
|
|
1) Hormones in Treatment of
Psychoses. In BMJ, November 1972.
Letter to the BMJ editor from W. Bujanov, Vyborg Medica Dispensaire (Leningrad,
URRS) in regards to the administration of hCG i the treatment of
affective disorders and tension with depression.
|
|
2) Functional Anatomy of the
Hypothalamus and Pituitary. In Basic and Clinical Neurosciences 28th
Annual Postgraduate Review Course. December 2005.
Hypothalamus overview, afferent and eferent connections, structures of
neuroendocrine control, functions of the Hypothalamus, temperature
control and its dysfunction, water and osmotic balance, circandian
rhythms, fear, rage and pleasure, research on hypothalamic therapy and
pituitary function.
|
|
|
|
|
|
In Spanish
|
|
|
|
|
|
